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Knowledge for Use in Practice

29–31 March 2023            at Rīga Stradiņš University & online

Innovation in Medicine and Healthcare – from Research to Practice

Topics
  • Digital Transformation in Healthcare
  • Precision medicine
  • Digital innovations
  • Telemedicine
Agenda – Wednesday, 29 March

Venue: RSU Medical Education Technology Centre, 26A Anniņmuižas bulvāris

9:00-9:10

Modern Fluorescence Microscopy: a Tool to See the Nano-details of Life
Rinalds Seržants

9.10 - 9.20

The Multi-Step Clinical Protocol for a Novel Pharmacological Dosage Monitoring Device Research
Antons Miscenko

9.20 - 9.30

Health professionals’ digital competencies and experiences with use of digital technology in rehabilitation sector
Aleksandrs Grjadovojs

9.30 - 9.40

Analysis of machine learning models for using self- evaluation questions to predict scores of depression, anxiety and stress in cardiovascular patients
Renars Erts

9.40 - 9.50

Prediction of Sepsis using Machine Learning Methods on MIMIC-III Database
Nazli Shahbazi

9.50 - 10.00

The Automated IoT System for the Gsk Ellipta Inhaler to Asses Patient Adherence
Antons Miscenko

10.00 - 10.10

A comparison of machine learning model with human subjects to correctly identify adventitious lung sounds
Haroldas Razvadauskas

10.10 - 10.20

Phantom Pain Management and Creation of Sensory Phantom Map of Hand Using Virtual Reality Robotic System
Dr. Dace Dimante

10:20-10:30

Break

10:30-11:00

Digital twin, metaverse, artificial intelligence and other 5G technologies for health
Elina Lidere
LMT Innovations Ecosystems Lead

11:00-12:00

The Value Day session “Digital Transformation in Healthcare” (Giving lecture remotely)
Koen Kas
Health futurist, Professor, Author, Keynote Speaker, Delight Thinker, CEO of Healthskouts


During this session you will have the unique opportunity to learn about:

  • global trends and hot topics in healthcare
  • inspiring examples and lessons from the COVID-19 pandemic
  • resilience of the healthcare system - against pandemic, but also climate change & other disruption
  • empowering & delighting citizens through choice, personalization, trust & transparency
  • equality & social determinants of health
  • public authorities as Innovation/Science hubs and Data-driven care
  • recommended roadmap for digitization: how to build sustainable and digitally enabled healthcare services

Moderator: Baiba Ziemele, Latvian Network of Patient Organizations

30-minute interaction with panelists. Q&A

12:00-12:30

Break

12:30-13:00

Precision medicine: progress of the legislation and results

Participants – deputy state secretaries:

  • Raimonds Lapiņš, Ministry of Economics
  • Gatis Ozols, Ministry of Environmental Protection and Regional Development
  • Aiga Balode, Ministry of Health

Moderator: Baiba Ziemele, Latvian Network of Patient Organizations

13:00-13:10

Precision medicine networking forum 2023
Roberts Melbārdis, Director of the Precision medicine networking forum 2023

13:10-13:30

Break

13:30-14:30

Knowledge transfer from ARC – the centre for digital innovation at Sheba medical centre
Moderator: Ieva Siliņa, Ministry of Economics

Participants:

  • ARC representatives (TBC)
  • Raimonds Lapiņš, Ministry of Economics
  • Agrita Kiopa, Rīga Stradiņš University
  • Children`s Clinical University Hospital representative

14:30-15:00

Break

15:00-16:00

Future of telemedicine
Ruthy Kaidar, Microsoft

Moderator: Rauls Vēliņš, Roche

Participants:
Māris Dreimanis, National Health Service
Baiba Ziemele, Latvian Network of Patient Organizations
Dins Šmits, Rīga Stradiņš University

16:00-17:00

Europe data hub. Saving lives with Big data and AI

Participants:  Raimonds Lapiņš (Ministry of Economics), Tomasz Kopacz (Microsoft), Emils Sundjukovs (Longenesis), Rolands Lappuķe (Advisor to the President), Mārcis Leja (University of Latvia)

Scientific Committee
  • Raimonds Lapiņš, Ministry of Economics
  • Agrita Kiopa, RSU Vice-Rector for Science  
  • Elīna Dimiņa, Development Manager at Children's Clinical University Hospital
  • Kaspars Rožkalns, Investment and Development Agency of Latvia
  • Baiba Ziemele, Patient Organization Network in Latvia
  • Laura Dabare, Ministry of Economics
Keynote Speakers

Women's and Children's Health

Topics
  • Gynecology & Obstetrics
  • Pediatrics
  • Neonatology
Agenda – Wednesday, 29 March

Venue: RSU Pharmaceutical Education and Research Centre, 21 Konsula iela, 1st floor, Room #204

Session I: Children's Health
Moderators: Prof. Dace Gardovska, Prof. Jana Pavāre, Assoc. Prof. Daina Dreimane
9:00–9:30From Pandemic to Tripledemic: Experience and Adaptation in a Children’s Hospital
Matthew I. Goldsmith, M.D.
9:30–10:00Discovering Genetic Basis of Early Onset Childhood Obesity
Daina Dreimane, M.D., and Marcos Caprile, M.S.II
10:00–10:10Short and Mid-Term Outcomes of Multysystem Inflammatory Syndrome In Children (Mis-C): Prospective Longitudinal Cohort Study
Ieva Roģe
10:10–10:20Children's Rights-Based Pain Management Strategy
Polina Popeiko
10:20–10:30Comparision of Primary Clinical Manifestation of Type I Diabetes in Children With and Without Previous Exposure to SARS-CoV-2 Virus
Lizete Kļaviņa
10:30–11:00Break
Session II: Children's Health
Moderators: Prof. Ilze Grope, Assoc. Prof. Zane Ābola, Prof. Henriette A. Moll
11:00–11:30Maintenance Fluids and Rehydration Fluids. Can We Use the Same Strategy?
Prof. Corsino Rey Galán
11:30–12:00Febrile Children at the Emergency Department: Early Recognition of Serious Bacterial Infections
Prof. Henriette A. Moll
12:00–12:10Clinical, Molecular Biological, and Microbiological Integrated Investigation in the Case of Paediatric Acute Complicated and Uncomplicated Appendicitis
Mohit Kakar
12:10–12:20Invasive Pneumococcal Disease and S. pneumonia Carriage in Hospitalised Children in Latvia 2018–2022
Mareks Marčuks
12:20–12:30Parents’ Knowledge About Fever in Children
Sandra Milta
12:30–13:30Break
Session III: Women's and Children's Health
Moderators: Prof. Dace Rezeberga, Assoc. Prof. Iveta Dzīvīte-Krišāne, Assoc. Prof. Noël C. Barengo
13:30–13:50The Epidemiology of Type 1 and Type 2 Diabetes in Children
Noël C. Barengo
13:50–14:00Sepsis-Associated Blood Sampling Causes Significant Blood Loss in Neonates
Dace Sniedze
14:00–14:10Supraventricular Tachycardia in Newborns in Children's Clinical University Hospital (2015–2020)
Jūlija Boroņenko
14:10–14:20Comparison of Impaired Adaptation of the Term Neonates After Spontaneous or Induced Labor in the High-Risk III Level Perinatal Center
Karīna Mahļina
14:20–14:30Therapeutic Hypothermia in Newborns Born with Asphyxia: Experience in the Biggest Latvian Perinatal Care Centre
Kristīne Rasnača
14:30–14:40Labor Induction – Is It Safe?
Anna Miskova
14:40–14:50Women's Suggestions Related to Experience of Care: A Qualitative Study in Latvia Using WHO Standards as a Framework for Analysis
Dārta Jakovicka
14:50–15:00Women's Suggestions on How to Improve the Quality of Breastfeeding and Support at the Hospital: A Qualitative Study in Latvia Using WHO Standards as a Framework for Analysis
Elīna Voitehoviča
Session IV
Moderators: Prof. Gunta Lazdāne, Assoc. Prof. Anna Miskova
15:30–15:40Association Between High-Risk HPV E6/E7 mRNA Expression and the Severity of Cervical Precancerous Lesions
Olga Plisko
15:40–15:50Factors Associated with High-Risk Human Papillomavirus Infection in Latvian Women
Natālija Bērza
15:50–16:00Assessment for Subtle Collagenopathy Predicts Preterm Birth Among Pregnant Women with Short Cervix
Anna Kornete
16:00–16:10Assessment of Medical Specialists’ Knowledge and Attitudes Towards Non-Invasive Prenatal Test (NIPT)
Greta Kuncaitytė
16:10–16:20Validation of the Childbirth Experience Questionnaire (CEQ) in Latvia
Agnija Vecvagare
16:20–16:30Cavernous Hemangioma of Uterine Cervix in Pregnancy: Report of a Rare Case
Jekaterina Stankeviča
16:30–16:50New Cevelopment in Contraception
Prof. Kristina Gemzell Danielsson
16:50–17:00Discussion
Scientific Commitee
  • Prof. Dr. habil. med. Dace Gardovska, Head of the Department of Paediatrics, RSU, Latvia
  • Prof. Jana Pavāre, Dean, Faculty of Medicine, Department of Paediatrics, RSU, Latvia
  • Prof. Ilze Grope, Dean, Faculty of Residency, RSU; Department of Paediatrics, RSU, Latvia
  • Prof. Dace Zavadska, Faculty of Medicine, Department of Paediatrics, RSU, Latvia
  • Prof. Valda Staneviča, Faculty of Medicine, Department of Paediatrics, RSU, Latvia
  • Assoc. Prof. Iveta Dzivite-Krišāne, Faculty of Medicine, Department of Paediatrics, RSU, Latvia
  • Assoc. Prof. Ingūna Lubaua, Faculty of Medicine, Department of Paediatrics, RSU, Latvia
  • Prof. Corsino Rey Galán, PhD, MD, University of Oviedo, Spain
  • Prof. Matthew Goldsmith, Washington University School of Medicine, Department of Pediatrics, Medical Director, Pediatric Intensive Care, St. Louis Children’s Hospital, USA
  • Assoc. Prof. Noël C Barengo, MD, PhD, MPH, Translational Medicine Herbert Wertheim College of Medicine, USA
  • Prof. Dace Rezeberga, Head of the Department of Obstetrics and Gynaecology, RSU, Latvia
  • Prof. PhD Gunta Lazdāne, Department of Obstetrics and Gynaecology; Director at Institute of Public Health, RSU, Latvia
  • Assoc. Prof. Anna Miskova, Department of Obstetrics and Gynaecology; Director at Institute of Public Health, RSU, Latvia
  • Assoc. Prof. Jana Žodžika, Department of Obstetrics and Gynaecology; Director at Institute of Public Health, RSU, Latvia
  • Assoc. Prof. Natālija Vedmedovska, Department of Obstetrics and Gynaecology; Director at Institute of Public Health, RSU, Latvia
  • Assoc. Prof. Kristina Jariene, Lithuanian University of Health Sciences, Lithuania
  • Prof. Kristina Gemzell Danielsson, Head of the Department of Women’s and Children’s Health, Karolinska Institutet, Sweden
Keynote Speakers

Oncology, Hematology, Precision Medicine, Rare Diseases, Morphology, Pathology Section

Topics
  • Oncology
  • Hematology
  • Precision Medicine
  • Rare Diseases, Rare cases
  • Morphology and Pathology
Agenda – Wednesday, 29 March

Venue: RSU, 16 Dzirciema iela, Lecture Hall #2

Session I: Oncology
Moderators: Prof. Jānis Gardovskis, Prof. Edvīns Miklaševičs
9:00–9:45Progress in BRCA1/2 Research Including PRS Role
Prof. Antonis Antoniou, University of Cambridge
9:45–10:00A Simulation of Effectiveness of Secondary Risk-Reducing Strategies in Carriers of Pathogenic Variants of BRCA1 and BRCA2 with Unilateral Primary Breast Cancer After Breast-Conserving Surgery
Jeļena Maksimenko
10:00–10:15A Spectrum and Frequency of CHEK2 Variants in Breast Cancer in Latvia: Initial Results and Literature Review
Arvīds Irmejs
10:15–10:30Can Serum HER2 after Two Neoadjuvant Chemotherapy Cycles Predict Pathologic Complete Response in Patients with HER2 Positive Early Breast Cancer?
Jelizaveta Kuzmina
10:30–11:00Break
Session II: Oncology
Moderators: Assoc. Prof. Zanda Daneberga, Prof. Arvīds Irmejs
11:00–11:15Urinary Exosomal miRNA Profiles as Markers of Bladder Cancer Development
Miki Nakazawa-Miklaseviča
11:15–11:30Modulation of microRNAs and tRNA‑Derived ncRNAs Expression Levels After Asbestiform Fibers Exposure in Mesothelial and Mesothelioma Cell Lines
Veronica Filetti
11:30–11:45Expression Pattern of Extracellular Matrix Genes in Benign and Malignant Neoplasms of the Prostate Gland
Tetiana Borikun
11:45–12:00Early Recurrence After Liver Resection in Patients with Colorectal Cancer Liver Metastases
Pāvils Plūme
12:00–12:15Focal Therapy Options in the Treatment of Primary Localized Prostate Cancer: Literature Review
Reinis Riekstiņš
12:15–12:30Identifying Genetic Factors Associated with Breast or Ovarian Cancer Risk in BRCA1 Pathogenic Variant Carriers
Egija Berga-Švītiņa
12:30–13:30Break
Session III: Molecular Biology/ Personalized (Precision) medicine
Moderators: Assoc. Prof. Zanda Daneberga, Dr. med. Linda Eglīte
13:30–13:45Hpv 16 E6-Based DNA Immunization Hinders Growth and Metastatic Activity Of E6/E7 Expressing Cancer Cells by Inducing Specific Cd4+ T-Cell Response and Reducing the Inflammatory Background
Juris Jansons
13:45–14:00Gene Expression Patterns as Useful Biomarkers for TNBC Patients
Elza Kuzņecova
14:00–14:15The Effect of Curcumin-Loaded Polymeric Nanoparticles on Ischaemia-Reperfusion (I/R) Injury in Primary Rat Cardiomyocyte Culture
Vytenis Keturakis
14:15–14:30Increased DNA Copy Number of LINE-1 and MSRV Transposable Elements Association with Male Infertility
Marija Lazovska
14:30–14:45Correlation of Procalcitonin and C-Reactive Protein Levels. Features in SIRS
Doina Dudnic
14:45–15:00Neutrophil-to-Lymphocyte and Lymphocyte-to-Monocyte Ratios as Inflammation Markers: a Large Cohort Study
Sergey Nikulshin
15:00–15:30Break
Session IV: Molecular Biology/ Personalized (Precision) medicine
15:30–16:30Pfizer Satellite Symposium
Agenda – Thursday, 30 March

Venue: RSU, 16 Dzirciema iela, Lecture Hall #2

Session I: Morphology, Oncopathology, Hematology
Moderator: Prof. Māra Pilmane
9:00–9:30Development of the Earliest Human Haematopoietic Stem Cells: From Embryo Dissections to Transcriptomics
Andrejs Ivanovs, UK
9:30–10:00Radiation Damage to the Eye – the Ratio of Morphological Changes and Functional Losses
Pavlo Fedirko, Ukraine
10:00–10:30Cancer Stem Cells
Ilze Štrumfa, Latvia
10:30–11:00Break
Session II: Morphology
Moderator: Prof. Ilze Štrumfa
11:00–11:15Right Atrial Morphology in Coronary Heart Disease and Degenerative Aortic Valve Stenosis
Edīte Vārtiņa, Latvia
11:15–11:30Findings of Different Tissue Factors and Apoptosis in Primary Obstructive Megaureter
Anna Junga, Latvia
11:30–11:45Tissue Phenomena and Their Possible Explanation
Māra Pilmane, Latvia
11:45–12:00Examination of Inflammatory and Anti-Inflammatory Cytokines and Factors in Milk of Dairy Cattle with Different Health Status of the Udder
Ksenija Šerstņova, Latvia
12:00–12:15Morphological Characterization of Pediatric and Adult Acquired Cholesteatoma
Kristaps Dambergs, Latvia
12:15–12:30Evaluation of Antimicrobial and Defence Proteins in Samples of Primary and Recurrent Nasal Polyps
Rūdolfs Vīksne, Latvia
12:30–13:30Break
Session III: Morphology
Moderator: Prof. Ilze Štrumfa
13:30–13:50Evaluation of Various Tissue Factors in the Bone of First and Second Time Performed Surgery (Osteoplasty and Rhinoplasty) in Cleft Lip Palate Patients
Dace Buile, Latvia
13:50–14:05PAX7, PAX9, SHH, SOX3, WNT3A and WNT9B Potential Role in Orofacial Cleft Affected Palatal Tissue
Jana Goida, Latvia
14:05–14:25Cleft Candidate Gene Protein Immunoreactivity in Human Non-Syndromic Cleft Affected Tissue
Mārtiņš Vaivads, Latvia
14:25–14:40Chromogenic in situ Hybridization (CISH): Experiences from Hisomorphological Research on Cleft Lip and Palate Tissue Samples
Nityanand Jain, Latvia
14:40–15:00Correlation Between Line-Field Confocal Optical Coherence Tomography and Histopatology. Preliminary Results
Doina Dudnic
14:45–15:00Neutrophil-to-Lymphocyte and Lymphocyte-to-Monocyte Ratios as Inflammation Markers: a Large Cohort Study
Rosario Caltabiano, Italy
15:00–15:30Break
Session IV: Morphology
Moderator: Prof. Māra Pilmane
15:30–15:50Digital Solutions in Pathology Education: Eight Years of Experience
Romans Uļjanovs, Latvia
15:50–16:10Histopathology of FLAIR Hyperintensity Zone and Cancer Stem Cell Distribution Between Enhancing Nodule and FLAIR Hyperintensity Zone in Glioblastoma, IDH-Wild Type: A Single-Institution Experience
Giuseppe Broggi, Italy
16:10–16:30Osteoarthritis ‒ the Entire Joint Disease
Valērija Groma, Latvia
16:30–16:45Detection of the Anatomical Variations of Human Occipital Condyles in Digital Visualizations
Dzintra Kažoka, Latvia
16:45–17:00Morphological Changes in Strabismus-Affected Eyeball Muscles in the Patient and in the Control Group
Vita Konopecka, Latvia
Agenda – Friday, 31 March

Venue: RSU, 16 Dzirciema iela, Lecture Hall #2

Session I: Rare Diseases / Rare Cases
Moderators: Assoc Prof. Andris Skride, Dr Valdis Ģībietis
9:00–9:05Opening
Assoc. Prof. Andris Skride
9:05–9:20Pulmonary Hypertension
Dr Matīss Šablinskis
9:20–9:35Different Faces of Amyloidosis
Dr Valdis Ģībietis
9:35–9:50Fabry Disease in Latvia. Is It So Rare?
Dr. med. Ainārs Rudzītis
9:50–10:05Autosomal Dominant Polycystic Renal Disease in Adults
Assoc. Prof. Ieva Ziediņa
10:05–10:20Congenital Complete A-V Block in Children
Prof. Inguna Lubaua
10:20–10:30Discussion
10:30–11:00Break
Session II: Rare Diseases / Rare Cases
Moderators: Assoc Prof. Andris Skride, Dr Valdis Ģībietis
11:00–11:15AstraZeneca Satellite Symposium. Myasthenia Gravis – What’s New?
Asst. Prof. Viktorija Ķēniņa
11:15–11:30Refractory Sarcoidosis
Dr Zaiga Kravale
11:30–11:45Cystic Fibrosis
Dr Elīna Aleksejeva
11:45–12:00Recurrent Respiratory Papillomatosis
Dr Jānis Zariņš
12:00–12:15Eagle Syndrome
Dr Renārs Deksnis
12:15–12:30Discussion
12:30–13:30Break
Session III: Rare Diseases / Rare Cases
Moderators: Assoc Prof. Andris Skride, Dr Valdis Ģībietis
13:30–13:45Clinical Signs and Risk Factor Analysis of Women Patients with INOCA. Data from Latvian Cardiac SPECT Registry
Barbara Vītola
13:45–14:00Additional Value of Repeated Assessment of Left Ventricular Function After ST-Elevation Myocardial Infarction
Laima Caunīte
14:00–14:15Triglyceride-Associated Coronary Lumen Area Increase in Patients Receiving Inclisiran as Add-on Lipid-Lowering Treatment
Baiba Kokina
14:15–14:30Diagnostic and Predictive Significance of Impedance Cardiography in Patients Hospitalized Due to Decompensated Chronic Heart Failure
 
14:30–14:45Mitochondrial Genome Variation Demonstrates Associations with Coronary Artery Disease and a Plethora of Well-Established Disease Risk Factors and Dietary Preferences
Aniket Sawant
Scientific Commitee
  • Prof. Jānis Gardovskis, Department of Surgery, Faculty of Medicine, RSU, Latvia
  • Prof. Sandra Lejniece, Dean, Department of Doctoral Studies, Head of Study Programme, Department of Internal Diseases, RSU, Latvia
  • Prof. Edvīns Miklaševičs, Faculty of Medicine, Department of Biology and Microbiology, RSU, Latvia
  • Prof. Māra Pilmane, Head of Department of Morphology, Director, Institute of Anatomy and Anthropology, RSU, Latvia
  • Assoc. Prof. Zanda Daneberga, Department of Biology and Microbiology, RSU, Latvia
  • Assoc. Prof. Andris Skride, Department of Internal Diseases, RSU, Latvia
  • Assoc. Prof. Maija Radziņa, Head of Radiology Research laboratory, RSU, Latvia
  • Assoc. Prof. Arvīds Irmejs, Department of Surgery, Faculty of Medicine, RSU, Latvia
  • Prof. Jacek Gronwald, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland
  • Ilze Štrumfa, Department of Pathology, Faculty of Medicine, RSU, Latvia
  • Andrejs Ivanovs, Edinburgh Cancer Centre, United Kingdom
Keynote Speakers

Metabolism and Cardiovascular Diseases

Topics
  • Cardiovascular Diseases
  • Metabolic and Endocrine Diseases
Agenda – Wednesday, 29 March

Venue: RSU, 16 Dzirciema iela, Lecture Hall #1

Session I: State of the Art in the Microbiota: New Interests and Strategies
Moderators: Prof. Ilze Konrāde, Prof. Maija Dambrova
9:00–10:00Liver-Heart Communication
Aldons J. Lusis, UCLA, USA
10:00–10:30“Gut it” – Latvian Microbiome Project
Janis Kloviņš, LU / BMC
10:30–11:00Break
Session II: Acylcarnitines in Health and Disease
Moderators: Prof. Ilze Konrāde, Prof. Aivars Lejnieks
11:00–11:30Fatty Acid Energy Metabolites Acylcarnitines: How Much Is Too Much?
Maija Dambrova, RSU / LIOS
11:30–12:00Statin-Induced Adverse Effects in Mitochondria: Evidence from HMGCR Knock-out Mice
Edgars Liepiņš, RSU / LIOS
12:00–12:30Meldonium Increases the Functional Capacity of Patients with Chronic Right Ventricular Failure
Dana Kigitoviča, RSU
12:30–13:30Break
Session III: From Lifestyle Changes to Efficacy Biomarkers
Moderators: Prof. Maija Dambrova, PhD Edgars Liepiņš
13:30–14:00Lifestyle Changes: How Small Steps Make Big Changes
Ilze Konrāde, RSU / RAKUS
14:00–14:30Trimethylamine N-oxide: Cardiometabolic Disease Risk Factor or Just an Osmolyte?
Melita Vidējā, RSU / LIOS
14:30–15:00Reflections on the Evolution of Human Metabolism
Līga Plakane, LU
15:00–15:30Break
Session IV: Short Presentations of Selected Abstracts
Moderators: Prof. Ilze Konrāde, Prof. Maija Dambrova
15:30–15:45The Metabolome as a Predictive Biomarker of Outcome of Induction of Labour
Laura Rācene
15:45–16:00A Novel Approach to Increase Omega-3 Polyunsaturated Fatty Acids for Cardiometabolic Disease Management
Baiba Gukalova
16:00–16:15Variations of Testosterone Level by Age, Time and Season in a Large Male Cohort
Sergey Nikulshin
16:15–16:30Novel Genetic Loci in the Pathogenesis of Autoimmune Thyroid Diseases and Their Relationship with Selenium Status
Sabīne Upmale
16:30–16:45What Is Found from Placing a Continuous Glucose Monitor in Overweight Non-Diabetic Reproductive Age Women with Insulin Resistance
Gita Erta
16:45–17:00Discussion
Agenda – Thursday, 30 March

Venue: RSU, 16 Dzirciema iela, Lecture Hall #1

Session I: Cardiomyopathies
Moderator: Prof. Oskars Kalējs, Assoc. Prof. Vladimirs Voicehovskis
9:00–9:30Cardiovascular Problems and Covid-19. The Problems Are and Remains
Prof. Oskars Kalējs
9:35–10:05GPx and MDA Oxidative Stress Markers and Severity of Depression as Predictives of Recurrent Stable Coronary Heart Disease
Dr. med. Tarass ivaščenko
10:10–10:25Tendencies in Oral Anticoagulant Usage for High-Risk Atrial Fibrillation Patients Over Period of 5 Years and Correlation with Survivability
Dr Ketija Apsīte
10:30–11:00Break
Session II: Sports Cardiology
Moderators: Prof. Oskars Kalējs, Asst. Prof. Kristīne Jubele
11:00–11:25Identification Program of Potential Cardiovascular Risk Factors of Veteran Athletes in Latvia
Dr Ketija Apsīte
11:30–11:55Program for Early Identification of Cardiovascular Risks in Young Athletes. Pilot Project
Dr Loreta Briuka
12:00–12:15Oregon Sudden Unexpected Death Study (SUDS) Electrocardiographic Risk Assessment of Sudden Cardiac Death for Master Athletes in Latvia
Dr Ketija Apsīte
12:15–12:30Discussion
12:30–13:30Break
Session III: Arrhythmias I
Moderators: Prof. Guido Claesen, Prof. Oskars Kalējs
13:30–13:55Identification of the Risk of Sudden Cardiac Death in Sports
Prof. Guido Claesen
14:00–14:25Genetic Aspects and Atrial Fibrillation
Dr Irina Rudaka
14:30–14:55Early Pulmonary Vein Isolation. Does It Matter?
Dr Kaspars Kupics
15:00–15:30Break
Session IV
Moderators: Asst. Prof. Kristīne Jubele, Prof. Aras Puožiukinas
15:30–Oral Anticoagulant Usage Among High-Risk Atrial Fibrillation Patients and Their Benefits
Dr Ketija Apsīte
16:00–TBA
Prof. Aras Puožiukinas
Agenda – Friday, 31 March

Venue: RSU, 16 Dzirciema iela, Lecture Hall #1

Session I
Moderators: TBD
9:00–9:45Drug Discovery and Bioexploration of Nature: Toxins, Friend or Foe?
Jan Tytgat, Katholieke Universiteit Leuven
9:45–10:00Vascular Tissue Genetics and Its Implications for Coronary Artery Disease
Baiba Vilne, RSU
10:00–10:15Exploring the Atherosclerotic Plaque Composition: From Intravascular Imaging to Molecular Profiling
Evija Knoka, RSU
10:15–10:30Detection of High Risk Coronary Plaques Using Invasive and Non-Invasive Imaging Modalities
Māris Lapšovs, RSU
10:30–11:00Break
Session II
Moderators: TBD
11:00–11:15High Risk Coronary Plaque Features – From Structural to Molecular Imaging
Marika Kalniņa, University of Latvia
11:15–11:45A Deep Virtual Dive into Coronary Arteries
Lucian Itu, Advanta, Siemens SRL & Department of Automation and Information Technology, Transilvania University of Brașov, Brasov, Romania
11:45–12:00Heart Valve Tissue Engineering: Back to the Future?
Mārtiņš Kalējs, RSU
12:00–12:30Is There Life After Life? Heart Transplantation
Pēteris Stradiņš, RSU
12:15–12:30Discussion
12:30–13:30Break
Session III
Moderators: TBD
13:30–13:45IPSEN Satellite Symposium. Neuroendocrine Tumors
Dr. med. Aija Geriņa-Bērziņa
13:45–14:00Hereditary Thrombocytopenia
Dr Artūrs Uzars
14:00–14:15Treatment Options in a Case of Latvian Patient with Hemophilia A and Inhibitors
Dr Žanna Kovaļova
14:15–14:30Paroxysmal Nocturnal Hemoglobinuria
Dr Vitālijs Ankudovičs
14:30–14:45Medis Satellite Symposium. Bile Acid Synthesis Disorders
Prof. Vaidotas Urbonas
14:45–15:00Discussion
Scientific Committee
  • Prof. Ilze Konrāde, Faculty of Medicine, Department of Internal Diseases, RSU, Latvia
  • Prof. Maija Dambrova, Department of Pharmaceutical Chemistry, RSU, Latvia
  • Prof. Oskars Kalējs, Department of Internal Diseases, RSU, Latvia
  • Assoc. Prof. Kārlis Trušinskis, Department of Internal Diseases, RSU, Latvia
  • Assoc. Prof. Pēteris Stradiņš, Department of Surgery, RSU, Latvia
  • Baiba Vilne, PhD, Head of Bioinformatics Lab, RSU, Latvia
Keynote Speakers

Mental Health and Neuroscience

Topics
  • Psychiatry
  • Neurology
  • Pediatric Neurology
  • Neuroradiology
  • Pain Medicine
  • Psychotherapy/Psychosomatics
Agenda – Wednesday, 29 March

Venue: RSU, 16 Dzirciema iela, Lecture Hall #3

Mental Health and Neuroscience Plenary Session
Moderators: Prof. Elmārs Rancāns, Prof. Andrejs Millers
9:00–9:40Pandemic Impact on Mental Health – Why Do We Need to Keep Talking About COVID-19?
Assoc. Prof. Jeļena Vrubļevska
9:40–10:10Neurological Manifestations of COVID-19 Infection
Ravita Gailāne, Prof. Guntis Karelis
10:10–10:30Neurological Complications Following SARS-CoV-2 Infection in Children
Sandis Kovaļovs, Aiga Zariņa, Marija Čehoviča, Inese Kazaine, Mikus Dīriks, Jurģis Strautmanis, Guntis Rozentāls
10:30–11:00Break
Session I: Neurocognitive and Perceptual Processes
Moderators: Asst. Jānis Mednieks, Jurģis Šķilters
11:00–11:25Similarity and Dissimilarity in Perceptual Organization: Toward a New Theory of Visual Information
Prof. Baingio Pinna
11:25–11:40Integrative Approach to Neurocognitive and Perceptual Processes
Jurģis Šķilters
11:40–11:55Current Approach to Alzheimer's Disease in Radiology and Other Neurodegenerative Diseases and Importance of Radiology in Clinical Trials of AD Drugs
Asst. Nauris Zdanovskis
11:55–12:10Early Changes in Various Cognitive Domains in Parkinson's Disease and Other Neurodegenerative Diseases
Asst. Jānis Mednieks
12:10–12:30Face Perception, Pareidolia and Emotions: From Holistic to Component Processing and Back
Jurģis Šķilters
12:30–13:30Break
Session II: Neuroradiology
Moderators: Assoc. Prof. Kārlis Kupčs, Assoc. Prof. Evija Miglāne
13:30–13:50Nerve Ultrasound as a Helpful Diagnostic Tool for Rare Hereditary Neuropathies' Evalution
Ronalds Linde
13:50–14:10Radiological Evaluation of Neurovascular Conflict in Trigeminal Neuralgia Patients with High-Resolution MRI: A Small case Series
Asst. Prof. Artūrs Balodis
14:10–14:30A Case Report of Diagnostic Difficulties in the Immunosupressed Patient with Suspected Primary Central Nervous System Lymphoma
Klinta Bičevska
14:30–14:50Myxopapillary Ependymoma with Extensive Local Invasion and Distant Dissemination. Therapeutic Dilemma
Asst. Prof. Artūrs Balodis
14:50–15:00Discussion
15:00–15:30Break
Session III: Paediatric Neurology
Moderators: Jurģis Strautmanis, Mikus Dīriks
15:30–15:40Paediatric Charcot-Marie-Tooth Disease: Longitudinal Evaluation of Potential Disease Progression Biomarkers
Signe Šetlere
15:40–16:00Vagal Nerve Stimulation for Epilepsy – Experience of Latvia
Dana Apela
16:00–16:20Arterial Ischemic Stroke in Childhood: Clinical Experience in Latvia
Sandis Kovaļovs
16:20–16:40Treatment Choice and Long-Term Outcome in Pediatric Autoimmune Encephalitis
Dace Pretkalniņa
16:40–17:00Epidemiological and Clinical Characteristics of Pediatric Onset Multiple Sclerosis in Latvia
Dace Pretkalniņa
Agenda – Thursday, 30 March

Venue: RSU, 16 Dzirciema iela, Lecture Hall #3

Session I: Mental Health
Moderator: Prof. Elmārs Rancāns, Assoc. Prof. Jeļena Vrubļevska
9:00–9:20Sex-Specific Differences in the Associated Factors of Depressive Symptoms: A Population-Based Study
Asst. (acting) Vineta Vinogradova
9:20–9:40Women’s Mental Health During the COVID-19 Pandemic: The World Experience and Latvian Data
Assoc. Prof. Jeļena Vrubļevska
9:40–10:00Burnout and Symptoms of Depression During COVID-19 Pandemic in Latvian Medical Residents
Dr Aļona Počopko
10:00–10:20Beliefs in Conspiracy Theories and Self-Reported Changes in Anxiety and Depression in the Sample of Latvian Students During the COVID-19 State of Emergency
Dr Jūlija Vorobjova
10:20–10:30Discussion
10:30–11:00Break
Session II: Mental Health
Moderators: Prof. Māris Taube, Asst. Prof. Ļubova Renemane
11:00–11:20Strengths and Difficulties Questionnaire (SDQ) as a Mental Health Screening Tool in General and Clinical Adolescent Populations in Latvia
Asst. Ņikita Bezborodovs
11:20–11:40Internal Validity of the Latvian Version of 16-Item Prodromal Questionnaire PQ-16 in Help-Seeking Population in Rīga Children's Clinical University Hospital Psychiatry Clinic: A First Step Description
Dr Ilana Germaņenko
11:40–12:00Patient Waiting Time in Latvian Psychiatric Outpatient Care: Protocol and Future Implementation
Asst. Liene Sīle
12:00–12:20Psychosocial Hazards and Preventative Measures for the Mental Health of Employees in Hospitals in Latvia
Kristīne Dudina
12:20–12:30Discussion
12:30–13:30Break
Session III: Psychotherapy and Psychosomatics
Moderators: Asst. Prof. Artūrs Utināns, Asst. Prof. Velga Sudraba
13:30–13:50The Relationship Between Information Sources and Perceived Risk Predictors on Protective Behaviour in Adults with Type 1 Diabetes During the Covid-19 Pandemic
Elīna Ieva Smule
13:50–14:10Resilience and Illness Denial as Predicting Factors of Adherent Behaviour for Patients With Chronic Illnesses in Primary Care
Gunita Skaldere-Darmudasa
14:10–14:30Physiotherapists' Needs for Continuous Education in Physiotherapy in Mental Health – a Qualitative Survey Analysis
Alise Berga-Kirilova
14:30–15:00Discussion
15:00–15:30Break
Session IV: Healthy Cognitive Aging
Moderator: Assoc. Prof. Ainārs Stepens
15:30–16:00Life-Style and Ageing: The Role of Daily Activities in Brain and Cognition
Prof. J. Rusted, C. Lancaster
16:00–16:15Combined Score of Perivascular Space Dilatation and White Matter Hyperintensities in Patients with Normal Cognition, Mild Cognitive Impairment and Dementia
Asst. Nauris Zdanovskis
16:15–16:30The Relationship Between Cognitive Reserve and Tempo-Parietal Cortical Regions in Older Adults
Asst. Kristīne Šneidere
16:30–16:45The Relationship Between Brain Atrophy, Motor Reserve and Global Cognitive Functioning in Older Adults
Milena Keistere
16:45–17:00Challenges in Mesauring Long-Term Physical Activity: The Development of the Motor Reserve Questionnaire
Gatis Upesleja
Agenda – Friday, 31 March

Venue: RSU, 16 Dzirciema iela, Lecture Hall #3

Session I: Pain Medicine
Moderators: Prof. Ināra Logina, Assoc. Prof. Eva Strīķe
9:00–9:25The Relevance and Importance of Acute Perioperative Pain: PAIN OUT Project
Prof. Winfried Meissner
9:25–9:40Patient Reported Acute Pain Treatment Outcomes in Hospital of Traumatology and Orthopaedics
Inta Čerņavska
9:40–9:55Scalp Nerve Block Following Craniotomy and Craniectomy in Pediatric Patients: A controlled Randomized Trial
Valdis Skotelis
9:55–10:10Efficacy of Erector Spine Plane Block in Two Different Approaches of Lumbar Spinal Fusion Surgery
Jānis Verners Birnbaums
10:10–10:20The Efficacy of Conservative Therapy, Interlaminar Epidural Steroid Injections and Their Both Combination in Relieving Severe Chronic Pain for Lumbar Central Spinal Stenosis
Viktorija Džabijeva
10:20–10:30Evaluation of the Effectiveness of Intra-Articular Steroid Administration in Patients with Hip Osteoarthritis
Andrejs Kostiks
10:30–11:00Break
Session II: Pain Medicine
Moderators: Prof. Ināra Logina, Assoc. Prof. Eva Strīķe
11:00–11:15Evaluation of  Primary Management of Headache Care in Latvia
Līga Mekša
11:15–11:25Interictal Correlations Between Body Mass Index and Cytokines Levels in Migraine
Aelita Plinta
11:25–11:40Expanding Phantom Limb Pain Treatment Possibilities Using Robot Assisted Virtual Reality System
Dace Dimante
11:40–11:55Pharmacotherapy for Polymorbid Patients with Chronic Musculoskeletal Pain: A Retrospective Study
Daniela Baumane
11:55–12:10Postoperative Pain Management in Patients Undergoing Intestinal or Colorectal Surgery for Non-Oncological Diseases
Līna Lāže
12:10–12:20Effectiveness of COX2 Inhibitor Etoricoxib Treatment on Pain in Patients with Arthritis
Prof. Ināra Logina
12:20–12:30Pregnancy-Related Abdominal Wall Neuropathy
Asst. Prof. Irina Evansa
12:30–13:30Break
Session III: Neurology
Moderators: Prof. Guntis Karelis, Asst. Prof. Daina Pastare
13:30–14:10Neurofilaments in Neurological Disorders – the Neurologist’s Multitool for Routine Diagnostic Work-up
Prof. Holger Schmidt, Elbe Kliniken Stade, Dpt. of Neurology, Germany
14:10–14:25Correlation Between SDMT and Functional Status in Multiple Sclerosis Patient
Arta Akmene, Elīna Polunosika, Daina Pastare, Rīga East University Hospital
14:25–14:40Use of Monoclonal Antibodies in Neurology in Rīga East University Hospital General Neurology Department
Marta Siliņa, Daina Pastare
14:40–14:55Peroral Disease-Modifying Drug Compliance Among Patients with Multiple Sclerosis in Rīga East Clinical University Hospital Multiple Sclerosis Unit
Natalija Buha, Monta Dāniele, Daina Pastare
Scientific Commitee
  • Prof. Elmārs Rancāns, Head of the Department of Psychiatry and Narcology, RSU
  • Prof. Andrejs Millers, Head of the Department of Neurology and Neurosurgery, RSU
  • Prof. Māris Taube, Department of Psychiatry and Narcology, RSU, Latvia
  • Prof. Douglas Ziedonis, Executive Vice President for UNM Health Sciences & Chief Executive Officer for the UNM Health System, University of New Mexico, USA
  • Assoc. Prof. Jeļena Vrubļevska, Department of Psychiatry and Narcology, RSU
  • Asst. Prof. Ļubova Renemane, Department of Psychiatry and Narcology, RSU
  • Asst. Ņikita Bezborodovs, Department of Psychiatry and Narcology, RSU
  • Asst. Prof. Daina Pastare, Department of Neurology and Neurosurgery, RSU
  • Asst. Prof. Elina Pūcīte, Department of Neurology and Neurosurgery, RSU
  • Assoc. Prof. Zanda Priede, Department of Neurology and Neurosurgery, RSU
  • Assoc. Prof. Evija Miglāne, Department of Neurology and Neurosurgery, RSU
  • Assoc. Prof. Kaspars Auslands, Department of Neurology and Neurosurgery, RSU
  • Asst. Jānis Mednieks, Department of Neurology and Neurosurgery, RSU
  • Assoc. Prof. (acting) Kārlis Kupčs, Department of Radiology, RSU
  • Asst. (acting) Jurģis Strautmanis, Department of Pediatrics, RSU
  • Asst. Prof. Artūrs Utināns, Department of Psychosomatic Medicine and Psychotherapy, RSU
  • Asst. Prof. Velga Sudraba, Department of Health Psychology and Paedagogy, RSU
  • Assoc. Prof. Ainārs Stepens, Military Medicine Research and Study Centre, RSU
  • Prof. Ināra Logina, Faculty of Residency, RSU
  • Assoc. Prof. Eva Strīķe, Department of Anaesthesiology and Intensive Care, RSU
  • Prof. Guntis Karelis, Department of Infectology, RSU
Keynote Speakers

Infectious Diseases, Immunity and Allergology

Topics
  • Infectious Diseases
  • Clinical Microbiology
  • Epidemiology
  • COVID-19
  • Vaccination
  • Infections in the development of non-communicable diseases
  • Autoimmunity
  • Allergology
Agenda – Wednesday, 29 March

Venue: RSU, 16 Dzirciema iela, Great Hall

Session I: Clinical Microbiology: Biofilm Formation, In Vitro Studies
Moderators: Prof. Juta Kroiča, Assoc. Prof. Ingus Skadiņš
9:00–9:25Biofilm Formation on Biomaterials and Anti-Biofilm Strategies
Ingus Skadiņš
9:30–9:45The Interaction of Antibiotics and Bacteriophages in Bacterial Biofilms
Laima Mukāne
9:45–10:00The Clinical Application of Bacteriophages in Complicated Biofilm-Associated Infections
Kārlis Rācenis
10:00–10:15Alternative to Prevent and Combat Biomaterial-Associated Infections: Clinically Recognized Bacteriophage-Based Biopolymer
Dace Rezevska
10:15–10:30Oral Biofilms and Mucosal Lesions in Smokeless Tobacco Users
Sintija Miļuna
10:30–11:00Break
Session II: Clinical microbiology: Biofilm Formation and Their Importance in the Body
Moderators: Prof. Aivars Pētersons, Assoc. Prof. Inese Mihailova
11:00–11:15Platelet-Rich Fibrin Antibacterial Activity Against Klebsiella Pneumoniae
Lana Mičko
11:15–11:30Biofilm Formation on Different Smooth and Textured Silicone Breast Implant Biomaterials
Kirils Jurševičs
11:30–11:45Bacterial Colonization and the Role of Bacterial Biofilms in the Upper Respiratory Tract
Renāta Vīksne
11:45–12:00The Role of Microbiome in Pathogenesis of Immunoglobulin A Nephropathy
Anna Popova
12:00–12:15The Significance of Clinical Presentations in the Course of the Immunoglobulin A Nephropathy (IgAN)
Viktorija Kuzema
12:15–12:30Dysregulated B Cell Responses in IgA Nephropathy
Kristīne Oļeiņika
12:30–13:30Break
Session III: Infections and Autoimmunity
Moderators: Prof. Yehuda Shoenfeld, Dr. med. Zaiga Nora-Krūkle
13:30–13:40Scientific Introduction
Yehuda Shoenfeld
13:40–14:10Molecular Mimicry as a Trigger of Autoimmunity
Dimitrios Bogdanos
14:10–14:30Autoimmune Diagnostics and Polymorphisms in Metabolic Enzymes
Marion Schnaider
14:30–14:45Latency and Reactivation of with Autoimmunity Associated Human Herpesviruses in COVID-19 Patients
Anda Vilmane
14:45–15:00Predominant Groups of Medical Conditions, Including Autoimmune Reactions, Represented in the Reporting of Suspected Adverse Reactions to COVID-19 Vaccines in the Eudravigilance Database
Diāna Arāja
15:00–15:30Break
Session IV: Infections and Autoimmunity
Moderators: Assoc. Prof. Modra Murovska, Prof. Angelika Krūmiņa
15:30–16:00Polyautoimmunity in Common Variable Immunodeficiency
Maria Giovanna Danieli
16:00–16:15Human Herpesvirus 6 – a Virus of Autoimmunity?
Lība Sokolovska
16:15–16:25Associated HHV-6 Viral Load and Changes in Immunologic Profile in Fibromyalgia
Lauma Ieviņa
16:25–16:35Epstein-Barr Virus in Multiple Sclerosis
Santa Rasa-Dzelzkalēja
16:35–16:50MiRNAs as Potential Biomarkers in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome
Irene Sofritti
16:50–17:00Towards Digital Ontology of ME/CFS in Self-Management and Assistance Applications
Uldis Berķis
Agenda – Thursday, 30 March

Venue: RSU, 16 Dzirciema iela, Great Hall

Session I: Vaccine-Preventable Infections and Diseases
Moderators: Prof. Dace Zavadska, Liene Čupāne
9:00–9:30Approach to Influenza Vaccinations in Children
Asst. Prof. Valtýr Stefánsson Thors, MD, PhD, Iceland
9:30–9:45Epidemiology of Invasive Pneumococcal Disease in Latvia in 2017–2021
Larisa Savrasova, RSU, CDPC
9:45–10:00Introduction of Novel Diagnostic Method for Detecting Natural-Only TBE Infections in Latvia – Current Challenges and Future Prospects
Zane Freimane, RSU
10:00–10:15Characteristics of Tick-Borne Encephalitis Without CNS Involvement
Prof. Guntis Karelis, RSU
10:15–10:30Effectiveness of TBE Vaccination in Latvia in 2018–2020
Prof. Dace Zavadska, RSU
10:30–11:00Break
Session II: Primary Immunodeficiency and Allergy
Moderator: Assoc. Prof. Nataļja Kurjane
11:00–11:15Primary Immunodeficiencies in Latvia
Assoc. Prof. Nataļja Kurjane, RSU
11:15–11:30First Results of Using Genome Sequencing in Discovering the Molecular Cause of Primary Immunodeficiencies
Linda Gailite, MD, PhD, RSU
11:30–11:45Opportunities of RNA-seg in the Molecular Diagnosis of Primary Immunodeficiencies
Katrīna Daila Neiburga, University of Tartu
11:45–12:00Altered Blood Metabolome in Hereditary Angioedema Patients
Kristaps Kļaviņš, PhD, RTU
12:00–12:15Allergy to Textile Dyes: Experimental and Clinical Research Data
Prof. Laura Malinauskiene, Lithuania
12:15–12:30Contact Allergy to the European Baseline Series in Lithuania
Kotrina Linauskiene MD, PhD, Lithuania
12:30–13:30Break
Session III: Primary Immunodeficiency and Allergy
Moderator: Assoc. Prof. Nataļja Kurjane
13:30–14:15Research Novelties in Chronic Spontaneous Urticaria
Prof. Marcus Maurer, Germany
14:15–15:00Allergic Manifistations and Allergy-Like Masks of Primary Immunodeficiencies
Prof. Anastasia Bondarenko, Ukraine
15:00–15:30Break
Session IV: Latest Developments and Contexts of Modern Infectology
Moderators: Prof. Ludmila Vīksna, Asst. Prof. Sniedze Laivacuma
15:30–15:40Changing Paradigms in Contemporary Infectology
Prof. Ludmila Vīksna, RSU
15:40–16:00Challenges in Search for Reliable Information on COVID-19: Experience of an Interdisciplinary Team from Latvia
Assoc. Prof. Aleksandrs Koļesovs, LU
16:00–16:20Long-Term Health Consequences 18–24 Months After Acute Covid-19 Among Hospitalized Patients
Ieva Vanaga, RSU
16:20–16:40Post-Covid Lung Recovery: Immunological Insights and Quality of Life
Edita Strumiliene, Vilnius University, Lithuania
16:40–17:00Diagnosis and Treatment of Cytomegalovirus Infection in the GUT: Current Dilemmas
Prof. Indra Zeltiņa, RSU
Agenda – Friday, 31 March

Venue: RSU, 16 Dzirciema iela, Great Hall

Session I: Latest Developments and Contexts of Modern Infectology
Moderators: Prof. Ludmila Vīksna, Assoc. Prof. Raimonds Sīmanis
9:00–9:15Covid-19 Infection in Pregnant Women – Experience of the Latvian Tertiary Level University Hospital
Maira Jansone
9:15–9:35Acute Cerebral Infarction and Covid-19 Infection in Inpatient Conditions at Latvian Tertiary Level University Hospital
Diāna Patrīcija Grosa
9:35–9:55Late Results of Corneal Transplantation in Cases of Infectious Keratitis
Prof. Guna Laganovska, RSU
9:55–10:15Differences in Fecal Microbiome Diversity and Liver-Related Markers in Patients with Chronic Hepatitis C, HIV, and HIV/HCV Coinfection
Monta Madelāne
10:15–10:30Seroprevalence of SARS-CoV-2 Antibodies Among Children in Children’s Clinical University Hospital, Rīga, Latvia
Krista Sapronova, RSU
10:30–11:00Break
Session II: Latest Developments and Contexts of Modern Infectology
Moderators: Prof. Ludmila Vīksna, Asst. Prof. Agita Jēruma
11:00–11:15Trends in Microbiological Spectrum and Antibiotic Resistance Pattern in Periprosthetic Joint Infections
Dace Vīgante
11:15–11:30Prevalence of Parasitic Infections with Zoonotic, Potential in Shrews, Rodents and Frogs in Latvia
Evita Grāvele
11:30–11:45Echinococcosis Risk Factors in Latvia and Neighbouring Countries
Prof. Sniedze Laivacuma, RSU / Rīga East Clinical University Hospital
11:45–12:05Anti-HCV Prevalence and Risk Factors in Patients of Psichiatry Hospitals and Social Care Centers in Latvia
Assoc. Prof. Ieva Tolmane, LU
12:05–12:20Analysis of Accumulated Single Nucleotide Variants and Mutation Rate in M. tuberculosis Isolate Pairs Using the Whole Genome Sequencing Approach
Darja Sadovska, Latvian Biomedical Research and Study Centre / RSU
12:20–12:30Closing
Prof. Ludmila Vīksna
Scientific Commitee
  • Dr. med. Zaiga Nora-Krūkle, Director, Institute of Microbiology and Virology, RSU, Latvia
  • Prof. Ludmila Vīksna, Head of the Department of Infectology, RSU, Latvia
  • Prof. Juta Kroiča, Head of the Department of Biology and Microbiology, RSU, Latvia
  • Prof. Dace Zavadska, Department of Paediatrics, RSU, Latvia
  • Dr. med. Anda Kadiša, Institute of Microbiology and Virology, RSU, Latvia
  • Assoc. Prof. Nataļja Kurjāne, Department of Biology and Microbiology, RSU, Latvia
  • Assoc. Prof. Ingus Skadiņš, Department of Biology and Microbiology, RSU, Latvia
  • Prof. Aivars Pētersons, Department of Internal Diseases, RSU, Latvia
  • Asst. Prof. Viktorija Ķēniņa, Department of Biology and Microbiology, RSU, Latvia
  • Prof. Marion Schneider, Head of the Division Experimental Anesthesiology, Ulm University Hospital, Department of Anaesthesiology and Intensive Care, Ulm, Germany
  • MD, PhD Boris Gilburd, The Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel HaShomer, Israel
  • Dr. med. Modra Murovska, Institute of Microbiology and Virology, RSU, Latvia
  • Dr. med. Alīna Sultanova, Institute of Microbiology and Virology, RSU, Latvia
  • Dr. biol. Irina Holodņuka, Institute of Microbiology and Virology, RSU, Latvia
  • Dr. med. Santa Rasa-Dzelzkalēja, Institute of Microbiology and Virology, RSU, Latvia
  • Assoc. Prof. Oksana Koļesova, Institute of Microbiology and Virology, RSU, Latvia
  • Dr. med. Šimons Svirskis, Institute of Microbiology and Virology, RSU, Latvia
Keynote Speakers

Sports Medicine, Orthopedics – Traumatology and Rehabilitation

Topics
  • Sports Medicine
  • Orthopedics and Trauma
  • Physical Medicine and Rehabilitation
Agenda – Wednesday, 29 March

Venue: RSU Pharmaceutical Education and Research Centre, 21 Konsula iela, Ground Floor, Room #104 or 106

Session I: Exercise is medicine (also for chronic diseases)
Moderator: Prof. Yannis Pitsiladis
9:00–9:30Personalized Sports Medicine and Sports to Live Long and Healthy
Sandra Rozenštoka, M.D.
9:30–10:00Cardiovascular Disease and Physical Exercise
Prof. Fabi Pigozzi, M.D.
10:00–10:10 
10:10–10:20Remotely Supervised High Intensity Interval Training in Patients with Breast Cancer Undergoing Neoadjuvant
Prof. Aija Klaviņa
10:20–10:30Gait Variability During Barefoot and Shod Walk Among Military Personnel
Darja Ņesteroviča
10:30–11:00Break
Session II: ECSS symposium. Exercise in healthy ageing – from metabolism to balance
Moderator: Asst. Prof. Dace Reihmane
11:00–11:10What Determines Healthy Aging?
Asst. Prof. Dace Reihmane
11:10–11:45Does Metabolism Age Well?
Prof. Flemming Dela
11:45–12:20Power It up! Role of High Intensity Exercise Interventions in the Management of Frail Older Adults
Assoc. Prof. Amelia Guadalupe Grau
12:20–12:30Open Discussion
12:30–13:30Break
Session III: Orthopaedics and Trauma
Moderators:
13:30–13:55Total Hip replacement in Hip Dysplasia
Prof. Tomáš Trč
13:55–14:15Key Factors for a Successful Arthroplasty Register: The Lithuanian Experience
Prof. Šarūnas Tarasevičius
14:15–14:30Outcomes of Simultaneous Bilateral Total Hip Arthroplasty. Single Surgeon Experience
Maksims Mihailovs
14:30–14:45Preliminary Results of Sacroplasty Surgery in Elderly Patients in Cases of Acute Traumatic Fracture of the Lateral Mass of the Sacrum
Agris Mertens
14:45–15:00Penetration of Prophylactic Cephazolin in Lumbar Intervertebral Disc During Microdiscectomy
Aleksejs Repņikovs
15:00–15:30Break
Session IV: Orthopaedics and Trauma
Moderators:
15:30–16:00The Development of Personalized 3D Orthopaedic Technologies at Yale School of Medicine
Daniel Wiznia, M.D.
16:00–16:15Implant Choice in Complex Revision Knee Arthroplasty
Una Bladiko
16:15–16:30Development of an Anatomical Optimized Intramedullary Nail for the Treatment of Proximal Extraarticular Tibia Fractures
Joerg Franke
16:30–16:45The Hidden Injury: Posterior Malleolus Fractures in Combination with Tibial Diaphyseal Fractures
Andris Džeriņš
16:45–17:00Calcaneal Fracture Treatment Using External Fixation Combined with Mini-Invasive Internal Fixation Methods
Igors Kolosovs
Agenda – Thursday, 30 March

Venue: RSU Pharmaceutical Education and Research Centre, 21 Konsula iela, Ground Floor, Room #104 or 106

Session I: Rehabilitation
Moderators: Guna Bērziņa, Matteo Lancini
9:00–9:30Robotics in Rehabilitation. From Prototype to Clinical Practice
Assoc. Prof. Matteo Lancini
9:30–9:45Effectiveness of a Telerehabilitation Program with a Novel Device for Treatment of Neck Pain. A Randomized Controlled Trial
Dr Andoni Carrasco Uribarren
9:45–10:00Comparison of Virtual Reality Game with 3D Headset and Online Yoga in Improving Functional Performance, Balance and Cognitive Functioning in Seniors: A Feasibility Study
Gints Peleckis
10:10–10:15Computer Vision-Based Smartphone Application for the Assessment of Forward Head Posture in Sitting Position: A Validity and Reliability Study
Dr Luis Ceballos-Laita
10:15–10:30The WalkAide Device in Gait Therapy for Stroke Patients
Peter Macej
10:30–11:00Break
Session II: Rehabilitation
Moderators: Guna Bērziņa, Aija Kļaviņa
11:00–11:30Technology-Based Interventions to Promote Personalized Healthy Lifestyle: Challenges and Concerns
Prof. Aija Kļaviņa
11:30–11:45Use of the Digital Assistant “Vigo” at Home Environment for Stroke Recovery: Focus Group Discussion with Specialists Working in Neurorehabilitation
Klinta Epalte
11:45–12:00Behavior of Daily Physical Activity in Seniors with Chronic Cardiovascular Disease: An Analysis of the Effects of Internal Factors
Ilze Straupe
12:00–12:15Online Aerobic Adapted Physical Activities for Improving Functioning and Quality of Life in Persons with Chronic Stroke
Elza Sebre
12:15–12:30Proprioception in Patients with Patellofemoral Pain Syndrome: Comparing the Effect of Closed and Opened Kinetic Chain Exercises
Alexandra Melisova
12:30–13:30Break
Session III: Return to sport
Moderator: Prof. Bülent Ülkar
13:30–14:00Groin Pain in Athlete
Theodora Papadopoulou, M.D.
14:00–14:30The Utility of Musculoskeletal Ultrasound in Sports Medicine
Prof. Levent Ozcakar, M.D.
14:30–14:40Indicators of Successful Jumping Ability Post-ACL Reconstruction
Dr Toms Jānis Eglītis
14:40–14:50Sports Related Injuries in Adolescent Athletes
Dr Gunita Vinčela
14:50–15:00DAid Smart Socks as Feedback for Foot Performance Evaluation of Female Athletes During “Single Leg Squat” Test
Anna Davidoviča
15:00–15:30Break
Session IV: High Achievement Sports
Moderator: Sandra Rozenštoka, M.D.
15:30–16:00The Limits of Athletes Adaptation
Prof. Bülent Ülkar, M.D.
16:00–16:30Doping and “Border” Technologies in Sports
Prof. Yannis Pitsiladis, PhD Exercise Biochemistry
16:30–16:40Latvia Women's National Football Team Health and Movement Pattern Analysis
Dr Gundega Akuratere
16:40–16:50Metabolic Flexibility and Lactate Profile in Maximal Treadmill Exercise Testing in Female Athletes
Dr Laila Ušacka
16:50–17:00Periodisation and High Intensity Interval Training in Endurance Sports, a Review
Dr Mārcis Jakovičs
Scientific Commitee
  • Assoc. Prof. Pēteris Studers, Department of Orthopaedics, Leading Researcher, Joint Laboratory of Traumatology and Orthopaedics, RSU, Latvia
  • Prof. Andris Jumtiņš, Head of Department of Orthopaedics, RSU, Latvia
  • Dr. med. Sandra Rozenštoka, lecturer, RSU, Latvia
  • Dr. med. Guna Bērziņa, Head of Department of Rehabilitation, RSU, Latvia
  • Asst. Prof. Dace Reihmane, Department of Human Physiology and Biochemistry, RSU, Latvia
  • Assoc. Prof. Signe Tomsone, Dean of the Faculty of Rehabilitation, RSU, Latvia
  • Asst. Prof. Daina Šmite, Department of Rehabilitation, RSU, Latvia
  • Asst. Prof. Gita Gersone, Department of  Department of Human Physiology and Biochemistry, RSU, Latvia
  • Prof. Bülent Ülkar, Sports Medicine Physician, Department of Sports Medicine, Ankara University Faculty of Medicine, Turkey
  • Asst. Prof. Andris Vikmanis, Department of Orthopaedics, RSU, Latvia
Keynote Speakers

Dentistry and Pharmacy

Topics
  • Dentistry
  • Orthodontics
  • Oral and Maxillofacial Surgery
  • Biomaterials
  • Pharmaceutical Science
Agenda – Thursday, 30 March

Venue: RSU Pharmaceutical Education and Research Centre, 21 Konsula iela, Room #204, 1st floor

Session I: Pharmacy
Moderators: Prof. Dace Bandere, Assoc. Prof. Baiba Mauriņa
9:00–9:10Evaluation of Antioxidant and Anti-Inflammatory Activity of Oat Milk and Yogurt Extracts
Inga Sīle
9:10–9:20The Impact of Extraction and Processing Methods on the Phenolic Acid Content of Two Genus Vaccinium Species
Ance Bārzdiņa
9:20–9:30Chemical Screening of Phenolic Compounds in Tansy Leaves Wild Growing in Different Conditions
Renāte Šukele
9:30–9:40Validation of Computational Fluid Dynamics Solver for Drug Dissolution and Transport in USP2 Apparatus
Normunds Jēkabsons
9:40–9:50Evaluation of Dispensing Medication Errors in Pharmaceutical Practice Among Direct Oral Anticoagulants Prescriptions
Anna Gavrilova
9:50–10:00Characteristics of Enterococcus Resistance Rate and Presence of Van Genes in Resistant Cultures from Two Multidisciplinary Hospitals in Latvia
Inga Mauliņa
10:00–10:10In vitro and ex vivo Levofloxacin Antibacterial Activity Against Escherichia Coli Isolated from Domestic Rabbits
Andrejs Šitovs
10:10–10:20Levofloxacin Antibacterial Activity Against Pasteurella Multocida Isolated from Domestic rabbits
Andrejs Šitovs
10:20–10:30Questions
10:30–11:00Break
Agenda – Friday, 31 March

Venue: RSU Pharmaceutical Education and Research Centre, 21 Konsula iela, Room #204, 1st floor

Session I: Dentistry
Moderators: Prof. Ilga Urtāne, Prof. Ilze Akota
9:05–9:17Regimes of SDF Compared with Tiefenfluorid for Severe Early Childhood Caries: A Randomised Clinical Trial
Dr Ilze Maldupa
9:17–9:29Pulp Revitalization Treatment of Young Permanent Teeth After TDI
Dr Egita Benefelde
9:29–9:41Facial Characteristics of Individuals with Crossbite
Dr Karlina Kienkas
9:41–9:53Automated Cephalometric Landmarks Positioning on Virtual 3d Models for Complex Maxillofacial Pre-Surgery Planning
Dr Deividas Blažys
9:53–10:05Report on New COST Project Ca 21140: Interception of Oral Cancer Development
Prof. Ingrīda Čēma
10:05–10:17Dysregulation of CD44 and p27 Antigens in Oral Leukoplakia
Dr Madara Dzudzilo
10:17–10:29Role of Epstein-Barr Virus in the Pathogenesis of Oral Lichen Planus
Dr Jagriti Kakar
10:30–11:00Break
Session II: Biomaterials / BBCE
Moderators: Assoc Prof. Anda Slaidiņa, Asst. Prof. Ilze Šalma
11:00–11:10Materials for Fixed Dental Prostheses Produced by Digital Manufacturing and Gingival Health: A Literature Review
Dr Elīna Blūma
11:10–11:20Fracture Resistance of Endodontically Treated Molars, Restored with Lithium Disilicate or Composite Overlays and Endocrowns
Sintija Miļuna
11:20–11:30Patient-Specific Titanium Implant Solution for Total Atrophic Upper Jaw. A Case Report
Dr Rihards Lācis
11:30–11:40An Effect of Three-Dimensional Printed Replica Use in Autotransplantation of an Immature Third Molar
Dr Miks Lejnieks
11:40–11:50Virtual Planning and Patient Specific Surgery Guides in Mandible and Maxillae Tumor Reconstruction with Free Fibula Flap
Dr Jānis Zariņš
11:50–12:00Retrospective Treatment Results of Isolated Orbital Floor Fractures Treated at Pauls Stradiņš Clinical University Hospital
Dr Uldis Spulle
12:00–12:10Platelet-Rich Fibrin Immunological Testing Using ELISA Assay 
Dr Lana Mičko
12:10–12:20Volumetric Changes of Malar Implants 12 Months After Augmentation
Dr Mārtiņš Lauskis
12:30–13:30Break
Session III: Diagnostic Value of Saliva
Moderators: Assoc Prof. Andris Ābeltiņš
13:30–14:30Keynote: Saliva Diagnostic Properties
Prof. Stefan Ruhl
Scientific Commitee
  • Assoc. Prof. Andris Ābeltiņš, Dean, Faculty of Dentistry, RSU, Latvia
  • Assoc. Prof. Dace Bandere, Dean, Faculty of Pharmacy, RSU, Latvia
  • Dr. med. Ilze Šalma, Department of Oral and Maxillofacial Surgery and Oral Medicine, RSU, Latvia
  • Prof. Ilze Akota, Department of Oral and Maxillofacial Surgery and Oral Medicine, RSU, Latvia
  • Prof. Ingīda Čēma, Department of Oral and Maxillofacial Surgery and Oral Medicine, RSU, Latvia
  • Prof. Una Soboļeva, Department of Prosthetic Dentistry, RSU, Latvia
  • Dr. Anete Vaškeviča, Department of Conservative Dentistry and Oral Health, RSU, Latvia
  • Inga Urtāne, Department of Pharmaceutical Chemistry, RSU, Latvia
  • Baiba Mauriņa, Department of Applied Pharmacy, RSU, Latvia
  • Prof. Maija Dambrova, Department of Pharmaceutical Chemistry, RSU, Latvia
  • Konstantīns Logviss, Faculty of Pharmacy, RSU, Latvia
Keynote Speakers

Other Sections

Topics
  • Basic Medical Science (Biochemistry, Physiology, Genetics, etc.)
  • Internal Medicine (Pulmonology, Gastroenterology, Nephrology, Rheumatology, etc.)
  • Imaging (Radiology)
  • Critical Care and Anesthesiology
  • Surgery
  • Urology
  • Ophthalmology
  • Otorhinolaryngology
  • Dermatology
  • Miscellaneous
History of Medicine – Friday, 31 March

Venue: RSU Anatomy Museum, 9 Kronvalda bulvāris, Conference Hall, 1st floor

Moderator: Prof. Juris Salaks
12:00–Maternity Hospitals in Latvia During the Soviet Period: Daugavpils
Maija Pozemkovska
 Regulatory Documents (Statutes) of the Latvian Red Cross (1918–1940)
Mārtiņš Vesperis
 Training of Military Medics ar Rīga Medical Institute for the Needs of the Soviet Army (1950–1990)
Daiga Dupate
 The Historical Learning Tool for Anatomy in the Collection of Rīga Stradiņš University Museum
Iveta Skripste
 Recent Acquisition of Unique Anatomical Objects at RSU Anatomy Museum
Ieva Lībiete
 Rīga Stradinš University Anatomy Museum Anthropological Survey Digitization Project
Diāna Jakseboga
 Unique Anthropology Data on Latvians in the 1930s: The Results of Primanis Expeditions
Lāsma Asare
 Materials for Fixed Dental Prostheses Produced by Digital Manufacturing and Gingival Health: A Literature Review
Dr Elīna Blūma
 Academician Jānis Stradiņš, the First Historiographer of the Museum of Medical History or Patron of the Museum?
Rita Grāvere
–14:00RSU History. Professor Georgs Andrejevs (1932–2022)
Kaspars Antonovičs

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